Drive a running Cytoscape Desktop to load, lay out, and style biological networks.
Connect Runs on your machine
claude mcp add cytoscape-desktop-mcp-bridge -e CYREST_PORT=<CYREST_PORT> -- https://github.com/cytoscape/cytoscape-desktop-mcp/releases/download/mcpb-v1.0.3/cytoscape-mcp.mcpb
{
"mcpServers": {
"cytoscape-desktop-mcp-bridge": {
"command": "https://github.com/cytoscape/cytoscape-desktop-mcp/releases/download/mcpb-v1.0.3/cytoscape-mcp.mcpb",
"args": [],
"env": {
"CYREST_PORT": "<CYREST_PORT>"
}
}
}
}
{
"mcpServers": {
"cytoscape-desktop-mcp-bridge": {
"command": "https://github.com/cytoscape/cytoscape-desktop-mcp/releases/download/mcpb-v1.0.3/cytoscape-mcp.mcpb",
"args": [],
"env": {
"CYREST_PORT": "<CYREST_PORT>"
}
}
}
}
{
"servers": {
"cytoscape-desktop-mcp-bridge": {
"type": "stdio",
"command": "https://github.com/cytoscape/cytoscape-desktop-mcp/releases/download/mcpb-v1.0.3/cytoscape-mcp.mcpb",
"args": [],
"env": {
"CYREST_PORT": "<CYREST_PORT>"
}
}
}
}
Replace the values in angle brackets with your own. Keys stay on your machine; we never see them.
Tools
This server runs locally, so its tools are listed by your MCP client once it starts.
Environment variables
| Name | Description |
|---|---|
CYREST_PORTOptional | Port Cytoscape Desktop's REST interface listens on (Edit > Preferences > REST API) |
Details
| Package | https://github.com/cytoscape/cytoscape-desktop-mcp/releases/download/mcpb-v1.0.3/cytoscape-mcp.mcpb (MCPB, stdio) |
| Package | @cytoscape/[email protected] (NPM, stdio) |
| First published | 11 Aug 2026 |
| Last updated | 11 Aug 2026 |
| Registry name | io.github.cytoscape/cytoscape-desktop-mcp-bridge |
More other servers See all
Listing data from the official MCP registry. Status and tools from NestDaddy's daily check. Browse all MCP servers.
