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BioCosm

io.github.nhoverte/biocosm · v1.0.0

Biotech intelligence for AI agents: drugs, targets, diagnostics, PoS estimates, and writeups.

Connect Remote server

Terminal
claude mcp add --transport http biocosm https://biocosm-mcp.fly.dev/mcp
~/.cursor/mcp.json
{
  "mcpServers": {
    "biocosm": {
      "url": "https://biocosm-mcp.fly.dev/mcp"
    }
  }
}
.vscode/mcp.json
{
  "servers": {
    "biocosm": {
      "type": "http",
      "url": "https://biocosm-mcp.fly.dev/mcp"
    }
  }
}
Claude Desktop
Settings > Connectors > Add custom connector
URL: https://biocosm-mcp.fly.dev/mcp

Tools 13 found in our last check

  • search_nodes

    Search BioCosm nodes by name, gene symbol, target, therapeutic area, or company. Results are ranked: exact name/brand matches first, then partial name matches, with a node-type prior (canonical drug/diagnostic nodes rank above gene-target nodes, which rank above ChEMBL salt-form…

  • get_node

    Get full details for a single BioCosm node: identity and all name aliases, classification, gene targets and mechanism, therapeutic areas, companies, revenue history where available (sparse: ~100 drugs, mostly blockbusters, as annualized quarterly estimates; source links when pre…

  • get_writeup

    Get the full writeup for a BioCosm node, including all sections, citations, structured data, and validation score.

  • list_by_therapeutic_area

    List all nodes in a given therapeutic area.

  • get_company_portfolio

    Get a company's full drug/diagnostic portfolio from BioCosm.

  • get_stats

    Get a high-level overview of the BioCosm database: total nodes, writeups, companies, breakdowns by type/status/domain, validation scores, and recent pipeline runs.

  • get_staleness_report

    Get writeup staleness report: overall stats, top stale nodes, data source freshness.

  • get_node_freshness

    Get freshness details for a single node: writeup age, enrichment hash match, staleness score, validation score.

  • find_by_target

    Find all drugs that target a specific gene/protein.

  • find_by_phase

    List drugs/diagnostics at a specific clinical phase.

  • find_related

    Find nodes connected to a given node. Three relationship types are derived on-the-fly: - "drug_target": for a drug, the targets it hits (and vice versa for a target node, the drugs that hit it) - "same_company": drugs sharing a company with this node - "same_target_class": drugs…

  • get_pos_score

    Get the Probability of Success estimate for a node, including the base rate, adjustment factors with reasoning, confidence interval, and model version. Returns None for nodes without a PoS score (typically only late-stage pipeline drugs are scored).

  • get_coverage

    Report BioCosm's actual data coverage so you never mistake missing data for a real-world zero. An empty or absent field on a node means "not in BioCosm's data," never a true zero. BioCosm is AI-generated and may contain errors.

Details

Endpointhttps://biocosm-mcp.fly.dev/mcp (Streamable HTTP)
First published17 Jun 2026
Last updated17 Jun 2026
Registry nameio.github.nhoverte/biocosm

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